Asymmetric Alcohol C–H Allylation andsyn-Crotylation: C9–C20 of Tetrafibricin
نویسندگان
چکیده
منابع مشابه
Diastereoselective allylation and crotylation of N-tert-butanesulfinyl imines with allylic alcohols.
The palladium-catalyzed allylation of N-tert-butanesulfinyl imines with allylic alcohols in the presence of InI as reducing reagent takes place with high diastereoselectivity in reasonable yields. The reaction with crotyl alcohol is totally regioselective, leading to the anti-diastereomer as the main reaction product.
متن کاملDiastereoselective allylation and crotylation of N-unsubstituted imines derived from ketones.
A wide variety of tertiary carbinamines are synthesized in high yields via diastereoselective allylation and crotylation of in situ generated N-unsubstituted ketimines.
متن کاملNi-catalyzed asymmetric reductive allylation of aldehydes with allylic carbonates.
This work features first asymmetric Ni-catalyzed reductive coupling of allylic carbonates with aldehydes, which may proceed via allyl-Ni intermediates although Zn was used as the terminal reductant. Moderate to excellent enantiomeric excess was obtained with excellent functional group tolerance.
متن کاملCu(I)-catalyzed asymmetric allylation of ketones and ketimines*
Chiral CuF-catalyzed asymmetric allylation of ketones and ketimines is described. Nucleophile activation via transmetallation (allylboronate to allylcopper), which is facilitated by a cocatalyst [La(OPr)3 or LiO iPr], is key for these reactions. A CuOTf–3KOtBu–DUPHOS complex is a comparably effective catalyst that reduces the required amount of chiral phosphines.
متن کاملCh-ch-ch-ch-Changes
Change is not made without inconvenience, even from worse to better. Richard Hooker, as quoted in the preface of Samuel Johnson's A Dictionary of the English Language Oh, so they have internet on computers now! Homer Simpson It is with great pleasure that I announce the rebirth of the former print journal of the Canadian Geriatrics Society as a new online publication, the Canadian Geriatrics Jo...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Organic Letters
سال: 2014
ISSN: 1523-7060,1523-7052
DOI: 10.1021/ol403566w